What should be done when hypertension drugs do not work?
Hypertension that does not respond to pharmacological treatment, the so called resistant form of hypertension, occurs very rarely. It is essential that the person see a specialist. More often, the reason for failure to see any effects of therapy is not following the doctor’s instructions and non-systematic administration of the prescribed drugs by patients. In addition, continuation of an unchanged lifestyle (alcohol, excess sodium in diet, obesity) may also limit the effectiveness of the treatment. The cause of an incorrect assessment of the results is the so called white coat hypertension. This term is used to define the increased blood pressure values that are seen only in measurements taken at the doctor’s office. Meanwhile, at home, the blood pressure is lower or even normal. After ruling out the above stated caused of therapy failure following 4-8 weeks of treatment the see p. 17). The next step is to change the drug to one belonging to a different group or, particularly recommended, to implement combined therapy, i.e. combing two or more drugs from different groups. It is believed, that a single drug (monotherapy) is sufficient to attain effective lowering of blood pressure in as many as 50% of patients. The remaining need combined therapy. The higher the values of blood pressure (I and II degree of hypertension) the more patients require combined form of thera